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Bioprocess Associate II - Protein Sciences

Bioprocess Associate II - Protein Sciences

Job Location 
Regular Full-Time

More information about this job


MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies.  Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases.  Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.


The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.

Summary of Position

The Bioprocess Associate II is responsible for all aspects of purification process development including process characterization and process transfer to the manufacturing group. In addition, the incumbent in this role will interact with other development functional leads to further process knowledge and resolve technical challenges.


Responsibilities and Job Duties:

  • Develop scalable purification processes for clinical phase biotechnology products
  • Execute bench scale experiments using depth filtration, column chromatography and UF/DF apparatus
  • Support technology transfer to manufacturing as needed
  • Perform analytical analysis such CE-SDS, SE-HPLC, CE-HPLC and SDS-PAGE
  • Identify and resolve difficult technical challenges within process development
  • Willingness to perform a significant amount of “hands on” laboratory work with high energy
  • Research ways to overcome challenges in the purification process
  • Timely and accurate documentation of work practices and processes


Education, Credentials and Experience

  • Bachelor’s degree in biochemistry, biology or related scientific discipline with a minimum of two years of related experience


  • Master’s degree in biochemistry, biology, or related scientific discipline. No experience required. 

Knowledge, Skills and Abilities

  • Downstream purification experience with hands on use of AKTA instrumentation, UFDF apparatus, HPLC instrumentation and other commonly used purification tools
  • Ability to troubleshoot equipment and purification processes as needed 
  • Ability to resolve complex problems within a fast paced environment
  • Excellent verbal and written communication skills in addition to strong organizational skills
  • Proven ability to handle multiple tasks and changing priorities in a fast-paced setting
  • Experience with process transfer from the development phase into manufacturing

Supervisory Responsibilities:



MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email or call (301) 354-3566 and/or 711 for TTD/TTY service.

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For more information about our commitment to equal employment opportunity, please click here.