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Research Associate II - Cell Biology

Research Associate II - Cell Biology

Job Location 
Regular Full-Time

More information about this job


MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies.  Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases.  Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.


The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.

Summary of Position

The Research Associate II will be part of a cell biology and immunology group focused on characterizing novel antibody-based therapies for the treatment of cancer and autoimmune disease. In this position you will be responsible for evaluating biological responses to candidate therapeutic molecules in a range of cell-based and immune-based assays.


Responsibilities and Job Duties:

  • Performs in vitro cell-based assays including primary cell assays and reporter assays to understand molecular structure/cell function relationships and to guide therapeutic molecule selection.
  • Maintains mammalian cell lines, ensuring necessary quality to support assay needs.
  • Isolates variety of cell types from human PBMC (T cell subpopulations, myeloid cells, B-cells etc) and employs in functional cell based assays.
  • Performs FACS analysis to investigate molecules’ binding properties and biological responses in different cell populations and reports results to supervisor. 
  • May create and develop new methods and technologies for project advancement.
  • Maintains written records of laboratory experiments, data, and conclusions. 


Education, Credentials & Experience


Bachelor’s Degree in scientific discipline with a minimum of two years of related experience or a Master’s Degree in a scientific discipline


Knowledge, Skills and Abilities

  • Proven working knowledge of basic cell biology techniques
  • General mammalian tissue culture
  • Experience with isolation of immune cells and executing cell-based assays including flow cytometry
  • Ability to work independently and be able to problem solve
  • Ability to multitask and work effectively with coworkers
  • Ability to communicate results effectively both written and orally
  • Capability in data analysis and data presentation are expected. 
  • Demonstrated ability to collaborate with other members of a team

Supervisory Responsibilities


Preferred Qualification:
Experience characterizing monoclonal antibodies including effector-function assays




MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email or call (301) 354-3566 and/or 711 for TTD/TTY service.

Equal Opportunity Employer/Veterans/Disabled


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