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Research Associate II/Associate Scientist I

Research Associate II/Associate Scientist I

Job Location 
Regular Full-Time

More information about this job


MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies.  Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases.  Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.


The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.

Summary of Position

The Research Associate II/Associate Scientist I will be part of the Antibody Engineering Group focused on generating novel antibody-based therapies for the treatment of cancer and autoimmune diseases. Candidates in this position will be responsible for performing hybridoma fusions, screening culture supernatants, subcloning and maintaining hybridoma cell lines, antibody purification, and cloning of V genes from hybridomas.

Responsibilities and Job Duties:

  • Schedule immunizations, prepare antigens, evaluate serum titers, and performs fusions
  • Screen and characterize antibodies for binding and functional activity (ELISA, FACS, biochemical and cell-based assays) 
  • Maintain, expand, cryopreserve, and clone hybridoma cell lines
  • Perform small scale antibody expression and purification of antibodies
  • Assist with molecular biology related tasks including cloning of V genes and generation of antibody expression plasmids
  • Maintain written records of laboratory experiments, data, and conclusions in compliance with all laboratory procedures





Education, Credentials & Experience


Research Associate II:


  • Bachelor’s Degree in scientific discipline with a minimum of two years of related experience or a Master’s Degree in a scientific discipline

Associate Scientist I:


  • Bachelor’s Degree in scientific discipline with a minimum of five years of related experience or a Master’s Degree in a scientific discipline with a minimum of two years of related experience

Knowledge, Skills and Abilities

  • Extensive experience in mammalian cell culture
  • Ability to maintain timely, detailed and accurate records of lab activities and follow lab protocols and procedures
  • Possess strong communication and organization skills and the ability to work in a team environment
  • Ability to work independently and be able to problem solve
  • Ability to multitask and work effectively with coworkers
  • Ability to analyze data and communicate results effectively both written and orally

Supervisory Responsibilities


Preferred Qualification:

  • Experience in screening assays such as ELISA or FACS
  • Previous experience in hybridoma generation and molecular biology techniques preferred


MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email or call (301) 354-3566 and/or 711 for TTD/TTY service.

Equal Opportunity Employer/Veterans/Disabled


For more information about our commitment to equal employment opportunity, please click here.